Table 3.

Group contrast analysis: Statistical significance for group differences in brain regional responses to viewing emotional faces (sad, angry, happy) and pictures of alcohol beverages and their location in Montreal Neurological Institute (MNI) space (mm); peak-level threshold of p_uncorrected< 0.001.

Region label	BA	Cluster size	T	Z	MNI coordinates
					x	y	z
Emotional faces
CTL>AUD
L. dorsolateral PFC, MFG, SFG	9	67	4.79*	4.46	−38	38	38
R. medial PFC	9	39	4.31	4.07	6	48	24
R. anterior PFC, MFG	10	105	4.15	3.93	24	58	26
L. Claustrum, Putamen		52	3.94	3.75	−30	0	8
R. SFG	8	33	3.81	3.63	18	26	54
R. Inferior OFG	47	31	3.67	3.51	48	26	−6
L. Anterior insula	13	69	3.57	3.42	−34	14	−4
AUD>CTL
R. Parahippocampal	36	18	3.62	3.46	40	−32	−16
R. Fusiform	37	11	3.60	3.45	46	−52	−12
R. Temporal lobe, MTG, STG	39	18	3.57	3.42	54	−64	16
L. Premotor cortex, SFG, MFG	6	14	3.53	3.39	−26	−8	64
L. Lingual, fusiform	18	15	3.46	3.33	−32	−70	−8
Alcoholic beverages
AUD>CTL
R. Inferior PFC, triangularis	47	11	3.46	3.33	54	32	0
Alcoholic beverages > non-alcoholic beverages
CTL>AUD
R. Anterior cingulate cortex	32	35	4.44	3.63	10	38	20

Abbreviations: BA, Brodman area; CTL, controls; AUD, alcohol use disorder; PFC, prefrontal cortex; MFG, middle frontal gyrus; SFG, superior frontal gyrus; OFG, orbitofrontal gyrus;

^*p_{FWE-corrected} <0.05.