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. Author manuscript; available in PMC: 2016 Nov 1.
Published in final edited form as: J Pathol. 2015 Jul 14;237(3):285–295. doi: 10.1002/path.4574

Figure 1.

Figure 1

Prolonged survival and mitigation of autoimmunity in CD47−/−–Faslpr mice. A) Genotyping by PCR. B) Proteinuria. Starting from age of 4 weeks (WK), mice were monitored for proteinuria at various time points (n=7). C) Cumulative survival of WT, CD47−/−Faslpr and CD47−/−–Faslpr mice (n=7). The difference was significant (P<0.01, log-rank test). D) PAS staining of kidney sections at age of 8 months (n=7). E) Immune staining of deposition of IgG, IgM, C3 and C1q in the glomeruli at age of 8 months (n=7). F) Quantitative analysis of IgG and IgM level, using 12–15 images collected from three mice. G) Quantitative analysis of C3 and C1q deposition in glomeruli, using 12–15 images collected from three mice. **, P<0.01.