Table VI.

Indications for the transfusion of fresh-frozen plasma.

- Neonates with ongoing bleeding and significant coagulopathy - Neonates with significant coagulopathy who must undergo invasive procedures - Congenital deficiency of clotting factors when the specific clotting factor is not available. Significant coagulopathy means prothrombin time (PT) and partial thromboplastin time (PTT) above normal limits or fibrinogen levels below the lower limit of normal for gestational age and post-natal age (Table VII).