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Intrathecal injection delivery of AAV vectors. (A) A diagram showing the AAV-shRNA vector used to target Nav1.3 in vivo (adapted from Samad et al., 2013 [5]). (B) A small laminectomy was performed between vertebral columns L5 and L6. AAV-vectors were then injected into intrathecal space and resulted in vector transduction of DRGs along the lumbar enlargement.
