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. 2015 Oct;185(10):2641–2652. doi: 10.1016/j.ajpath.2015.06.016

Figure 1.

Figure 1

Serum amyloid A1 (SAA1) is up-regulated in serum after brain injury. A: Western blot analysis showing SAA1 protein increase in serum at different time points after cortical impact injury (CCI) compared with control naïve mice. One representative experiment of five is shown. B: Quantitation of Western blot analyses showing SAA1 expression in serum was highest 6 hours after brain injury, with a smaller induction at 3 and 7 days after injury. SAA1 expression was normalized to glyceraldehyde-3-phosphate dehydrogenase (GAPDH). Values are expressed as means ± SEM (B). n = 5 to 8 per group (B). ∗∗P < 0.005, ∗∗∗∗P < 0.0001 for injured mice compared with control mice.