iNOS levels are up-regulated in UC. Gene expression of NOS2 (iNOS) in the CTRL, CD-, and UC-affected colon biopsies shows that iNOS levels are significantly higher in CD- and UC-affected biopsies than the control. Data are expressed as means ± SEM. ∗P < 0.05, ∗∗∗P < 0.001. Intergroup variance was evaluated with one-way analysis of variance significance test, and P values were obtained with t-test to demonstrate statistical significance between control group and CD group and control group and UC group. CD, Crohn disease; CTRL, control; iNOS, inducible nitric oxide synthase; UC, ulcerative colitis.