Table 5.
Association count | Multivariate LASSO association | |||
---|---|---|---|---|
Summary statistic | Patient | Control | Beta mean (SD) | Odds ratio mean (95% CI) |
Normalized SPL skew | 51 | 0 | 1.11 (0.04) | 3.03 (2.72–3.69) |
Normalized f0 95th percentile | 51 | 0 | 0.86 (0.03) | 2.36 (2.16–2.70) |
f0 skew | 51 | 0 | 0.53 (0.09) | 1.69 (1.42–2.35) |
Normalized SPL kurtosis | 51 | 0 | 0.28 (0.02) | 1.32 (1.22–1.44) |
Normalized SPL 5th percentile | 51 | 0 | 0.14 (0.03) | 1.16 (1.05–1.30) |
Normalized percent phonation | 51 | 0 | 0.12 (0.02) | 1.13 (1.07–1.20) |
Normalized f0 5th percentile | 0 | 50 | −0.10 (0.02) | 0.91 (0.85–1.00) |
Normalized SPL 95th percentile | 0 | 51 | −0.17 (0.03) | 0.84 (0.77–0.91) |
SPL kurtosis | 0 | 51 | −0.28 (0.02) | 0.76 (0.69–0.82) |
Normalized f0 skew | 0 | 51 | −0.41 (0.07) | 0.66 (0.51–0.77) |
SPL skew | 0 | 51 | −2.84 (0.12) | 0.06 (0.03–0.08) |
The maximum number that the “association count” field can have is 51. This occurs when that particular variable (row) has a statistically significant effect (p < 0.001, absolute average odds ratios ≥1.10) in each model. Many associations persisted across all models and also tended to agree well on the magnitude of the association. The 95% confidence interval (CI) is from the lowest bound across subsets to the highest bound across subsets.