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. 2015 Oct 16;5:15293. doi: 10.1038/srep15293

Table 1. DNA damage and its suppression during Cd-induced malignant transformation of 16HBE cells and siRNA/ENST00000414355 transfected 35th passage cells determined by comet assay.

Cell type DNA damage rate (%) Tail length (μm)
Untransformed 16HBE cells 4.75 12.8 ± 1.76
5th passage 10.45# 15.2 ± 3.54#
15th passage 22.00*# 31.6 ± 2.80*#
35th passage 46.75* 47.8 ± 2.36*
siRNA/ENST00000414355-4311 transfected 35th passage cells 24.79*# 33.8 ± 4.43*#
siRNA/ENST00000414355-4312 transfected 35th passage cells 23.98*# 32.4 ± 4.17*#
Negative control transfected 35th passage cells 41.14* 44.56 ± 5.17*

The tail lengths of cells in which DNA damage was induced and suppressed were determined by comet assay in untransformed 16HBE cells, 5th, 15th, 35th passage transformed cells, siRNA/ENST00000414355 transfected 35th passage cells and Negative control transfected 35th passage cells. *P<0.05, vs untransformed controls, #P<0.05, vs 35th passage cells.