Table 1. Main characteristics of all studies on the genotype of rs737008 included in the meta-analysis.
| First author (year) | Country | Ethnicity | Method | Control source | Cases/Controls | Case |
Control |
Case |
Control |
PHWE | MAF | ||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| CC | CA | AA | CC | CA | AA | C (%) | A (%) | C (%) | A (%) | ||||||||
| He XJ (2012) | China | Asian | MassARRAY | HP | 304/376 | 161 | 112 | 31 | 209 | 142 | 25 | 434 (71.38%) | 174 (28.62%) | 560 (74.47%) | 192 (25.53%) | 0.894 | 0.291 |
| Grassetti D (2012) | Italy | Caucasian | PCR sequence | HP | 110/53 | 15 | 55 | 40 | 4 | 29 | 20 | 85 (38.64%) | 135 (61.36%) | 37 (34.91%) | 69 (65.09%) | 0.137 | |
| Tuttelmann F (2010) | Germany | Caucasian | PCR sequence | PB | 171/77 | 23 | 63 | 85 | 8 | 28 | 41 | 109 (31.87%) | 233 (68.13%) | 44 (28.57%) | 110 (71.43%) | 0.338 | |
| Aoki VW (2006) | America | Caucasian | PCR sequence | HP | 192/96 | 32 | 79 | 81 | 12 | 43 | 41 | 143 (37.24%) | 241 (62.76%) | 67 (34.90%) | 125 (65.10%) | 0.889 | |
| Tanaka H (2003) | Japan | Asian | PCR sequence | PB | 226/270 | 125 | 86 | 15 | 129 | 117 | 24 | 336 (74.34%) | 116 (25.66%) | 375 (69.44%) | 165 (30.56%) | 0.729 | |
| Venkatesh S (2011) | India | Asian | PCR sequence | PB | 100/100 | 56 | 20 | 24 | 48 | 24 | 28 | 132 (66%) | 68 (34%) | 120 (60%) | 80 (40%) | 0.0001 | |
| Imken L (2009) | Morocco | Caucasian | PCR sequence | PB | 135/160 | 16 | 55 | 64 | 16 | 74 | 70 | 87 (32.22%) | 183 (67.78%) | 106 (33.13%) | 214 (66.88%) | 0.579 | |
| Jodar M (2010a) | Spain | Caucasian | PCR sequence | HP | 156/102 | 12 | 64 | 80 | 14 | 41 | 47 | 88 (28.21%) | 224 (71.79%) | 69 (33.82%) | 135 (66.18%) | 0.302 | |
| Jodar M (2010b) | Sweden | Caucasian | PCR sequence | HP | 53/50 | 2 | 28 | 23 | 4 | 20 | 26 | 32 (30.19%) | 74 (69.81%) | 28 (28%) | 72 (72%) | 0.955 | |
PCR sequence, polymerase chain reaction and sequencing.
HP, hospital population; PB, population based.
PHWE, Value of Hardy-Weinberg equilibrium in the control group.
MAF, Minimum allele frequency.