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. 2015 Oct 16;5:15300. doi: 10.1038/srep15300

Table 2. Main characteristics of all studies on the genotype of rs2301365 included in the meta-analysis.

First author (year) Country Ethnicity Method Control source Cases/Controls Case
Control
Case
Control
PHWE MAF
CC CA AA CC CA AA C (%) A (%) C (%) A (%)
He XJ (2012) China Asian MAssARRAY HP 304/369 187 100 17 241 112 16 474 (77.96%) 134 (22.04%) 594 (80.49%) 144 (19.51%) 0.518 0.222
YU QF (2012) China Asian MAssARRAY HP 157/37 61 70 26 17 19 1 192 (61.15%) 122 (38.85%) 53 (71.62%) 21 (28.38%) 0.109  
Gazquez C (2008) Spain Caucasian PCR-RFLP and sequence PB 220/101 114 90 16 68 30 3 318 (72.27%) 122 (27.73%) 166 (82.18%) 36 (17.82%) 0.888  
Imken L (2009) Morocco Caucasian PCR sequence PB 135/160 85 45 5 113 42 5 215 (79.63%) 55 (20.37%) 268 (83.75%) 52 (16.25%) 0.653  
Jodar M (2010a) Spain Caucasian PCR sequence HP 156/102 88 55 13 60 38 4 231 (74.04%) 81 (25.96%) 158 (77.45%) 46 (22.55%) 0.501  
Jodar M (2010b) Sweden Caucasian PCR sequence HP 53/50 25 27 1 26 17 7 77 (72.64) 29 (27.36%) 69 (69%) 31 (31%) 0.147  

PCR sequence, polymerase chain reaction and sequencing; PCR-RFLP, polymerase chain reaction-restriction fragment length polymorphism

HP, hospital population; PB, population based.

PHWE, Value of Hardy-Weinberg equilibrium in the control group.

MAF, Minimum allele frequency.