Table 3. Main characteristics of all studies on the genotype of rs1646022 included in the meta-analysis.
| First author (year) | Country | Ethnicity | Method | Control source | Cases/Controls | Case |
Control |
Case |
Control |
PHWE | MAF | ||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| GG | GC | CC | GG | GC | CC | G (%) | C (%) | G (%) | C (%) | ||||||||
| Grassetti D (2012) | Italy | Caucasian | PCR sequence | HP | 110/53 | 30 | 62 | 18 | 18 | 26 | 9 | 122 (55.45%) | 98 (44.55%) | 62 (58.49%) | 44 (41.51%) | 0.94 | 0.717 |
| Tuttelmann F (2010) | Germany | Caucasian | PCR sequence | PB | 159/73 | 57 | 66 | 36 | 22 | 28 | 23 | 180 (56.60%) | 138 (43.40%) | 72 (49.32%) | 74 (50.68%) | 0.047 | |
| Aoki VW (2006) | America | Caucasian | PCR sequence | HP | 192/96 | 76 | 85 | 31 | 39 | 44 | 13 | 242 (63.02%) | 142 (36.98%) | 124 (64.58%) | 68 (35.42%) | 0.985 | |
| Tanaka H (2003) | Japan | Asian | PCR sequence | PB | 226/269 | 127 | 80 | 19 | 127 | 118 | 24 | 334 (73.89%) | 118 (26.11%) | 372 (69.14%) | 166 (30.86%) | 0.646 | |
| Venkatesh S (2011) | India | Asian | PCR sequence | PB | 100/100 | 100 | 0 | 0 | 98 | 0 | 2 | 200 (100%) | 0 (0%) | 196 (98%) | 4 (2%) | 0 | |
| Jodar M (2010a) | Spain | Caucasian | PCR sequence | HP | 111/50 | 35 | 54 | 22 | 21 | 18 | 11 | 124 (55.86%) | 98 (44.14%) | 60 (60%) | 40 (40%) | 0.077 | |
PCR sequence, polymerase chain reaction and sequencing.
HP, hospital population; PB, population based.
PHWE, Value of Hardy-Weinberg equilibrium in the control group.
MAF, Minimum allele frequency.