Table 3. Associations between haematuria and clinical outcomes.

	Haematuria
	No	Mild	Moderate	P for trend
HR for ESRD
Unadjusted	1 (reference)	2.35 (1.94–2.85)**	2.30 (1.79–2.94)**	<0.001
Fully-adjusted	1 (reference)	1.28 (1.05–1.56)*	1.34 (1.03–1.74)*	0.024
OR for rapid renal function progression
Unadjusted	1 (reference)	1.77 (1.31–2.39)**	2.48 (1.76–3.49)**	<0.001
Fully-adjusted	1 (reference)	1.45 (1.05–2.00)*	1.54 (1.06–2.25)*	0.023
HR for all-cause mortality
Unadjusted	1 (reference)	1.59 (1.20–2.11)*	2.27 (1.64–3.14)**	<0.001
Fully-adjusted	1 (reference)	1.15 (0.86–1.54)	1.56 (1.11–2.20)*	0.039
HR for CV events
Unadjusted	1 (reference)	1.63 (1.09–2.45)*	1.72 (1.26–2.34)**	0.001
Fully-adjusted	1 (reference)	1.06 (0.70–1.63)	1.33 (0.97–1.82)	0.204

HR: hazard ratio, OR: odds ratio, CV: cardiovascular. Rapid renal function progression is defined as eGFR slope < −5 mL/min/1.73 m²/year.

Model adjusts for age, gender, eGFR, log-transformed UPCR, hypertension, cardiovascular disease, mean BP, BMI, hemoglobin, albumin, log-transformed cholesterol, log-transformed CRP and phosphorus.

*(P < 0.05) or **(P < 0.01) indicates a significantly different from reference group; P for trend <0.05 indicates a significant trend for haematuria.