Table 4.

Predictors of early recurrence after LT for HCC

Variable	Univariate analysis	Multivariate analysis
	P	HR (95 % CI) P
Age <60 years	0.022	1.27 (0.87–1.86) 0.217
Male sex	0.080
Hepatitis B virus infection	0.712
Pre-LT tumor therapy	0.203
AFP levels > 400 ng/mL	<0.001	1.71 (1.24–2.78) 0.001
Poor differentiation	0.020	1.31 (0.84–2.03) 0.232
Macrovascular invasion	<0.001	3.26 (2.29–4.64) <0.001
Microvascular invasion	<0.001	1.94 (1.40–2.71) <0.001
Beyond Milan criteria	<0.001	2.12 (1.41–3.20) <0.001
Blood transfusion	0.077
IBL > 4 L	<0.001	2.45 (1.64–3.66) <0.001