Table 1.
Comparisons Between Patients With Type 4 CRS and Controls
| Variables | CRS (n=17) | Controls (n=16) |
|---|---|---|
| Age, y | 70±11 | 62±9* |
| Female/male | 8/9 | 7/9 |
| Weight, kg | 58+14 | 63+17 |
| SBP, mm Hg | 143±21 | 129±14* |
| DBP, mm Hg | 76±8 | 79±11 |
| β-Blockers or RAAS inhibitors | 17/17 | 14/16 |
| Biochemical data | ||
| Urea, mmol/L | 18.2±9.1 | 4.8±1.3* |
| Creatinine, mg/dL | 458±291 | 81±13* |
| eGFR, mL/min | 34.2±17.7 | 84.44±5.3* |
| hs-CRP, mg/L | 28.3 (3.8 to 98.2) | 2.7 (1.3 to 3.5)* |
| NT-proBNP, pg/mL | 25 944 (4407 to 34 787) | 101 (49 to 219)* |
| Ang II, ng/L | 59.4 (46.1 to 84.4) | 39.8 (32.8 to 57.2)* |
| SOD, U/mL | 93±27 | 131±20* |
| Echocardiographic data | ||
| LVPWd, mm | 11.1±2.3 | 8.9±1.1* |
| IVSD, mm | 11.5±2.4 | 9.1±1.1* |
| LVEDD, mm | 57.2±9.2 | 46.2±2.2* |
| EF, % | 36.2±9.4 | 67.3±7.1* |
Data were expressed as mean±SD or median (interquartile range). CRS indicates cardiorenal syndrome; Ang II indicates angiotensin II; SBP, systolic blood pressure; DBP, diastolic blood pressure; RAAS, renin-angiotensin-aldosterone system; eGFR, estimated glomerular filtration rate; hs-CRP, high-sensitivity C-reactive protein; NT-proBNP, N-terminal pro-brain natriuretic peptide; SOD, superoxide dismutase; LVPWd, left ventricular posterior wall thickness at diastole; IVSD, interventricular septum depth; LVEDD, left ventricular end-diastolic diameter; EF, ejection fraction.
*
P<0.05 vs controls.