Table 1.

Contrasting the FRS and Pooled Cohort Equations

FRS			Pooled Cohort Equations
Outcomes modeled*			Outcomes modeled†
Terms	Male	Female	Male Terms	White Man	African American Man	Female Terms	White Woman	African American Woman
Ln age	3.06117	2.32888	Ln age	12.344	2.469	Ln age	−29.799	17.114
Ln TC	1.12370	1.20904	Ln TC	11.853	0.302	Ln TC	13.540	0.940
Ln HDL-C	−0.93263	−0.70833	Ln HDL-C	−7.990	−0.307	Ln HDL-C	−13.578	−18.920
Ln SBP treated	1.99881	2.82263	Ln SBP treated	1.797	1.916	Ln SBP treated	2.019	29.291
Ln SBP not treated	1.93303	2.76157	Ln SBP not treated	1.764	1.809	Ln SBP not treated	1.857	27.820
Smoking	0.65451	0.52873	Smoking	7.837	0.549	Smoking	7.574	0.691
Diabetes	0.57367	0.69154	Diabetes	0.658	0.645	Diabetes	0.661	0.874
			Ln age×Ln TC	−2.664	n/a	Ln age×Ln TC	−3.114	n/a
			Ln age×Ln HDL-C	1.767	n/a	Ln age×Ln HDL-C	3.149	4.475
			Ln age×smoking	−1.795	n/a	Ln age×Ln SBP treated	n/a	−6.432
						Ln age×Ln SBP not treated	n/a	−6.087
						Ln age×current smoker	−1.665	n/a
						Ln age squared	4.884	n/a

FRS indicates Framingham Risk Score; HDL-C, high-density lipoprotein cholesterol; Ln, natural log; SBP, systolic blood pressure; TC, total cholesterol.

^*Coronary death, myocardial infarction, coronary insufficiency, angina, cerebrovascular events (including ischemic stroke, hemorrhagic stroke, and transient ischemic attack), peripheral artery disease (intermittent claudication), and heart failure (see reference ³ for more details).

^†Coronary heart disease death, nonfatal myocardial infarction, and fatal and nonfatal stroke (see reference ⁴ for more details).