Hemodynamic response to exercise with regard to pulmonary and intracardiac pressures prior to and 1 year after HT. • Patients aged ≤50 years prior to HT. ○ Patients aged ≤50 years 1 year after HT. ▾ Patients aged >50 years prior to HT; Δ Patients aged >50 years 1 year after HT. ▪ All 32 patients prior to HT. □ All 32 patients 1 year after HT. A, MPAP. B, PAWP. C, MRAP. D, TPG. †A statistically significant difference for MPAP during exercise between patients aged ≤50 and >50 years. ‡A statistically significant difference for MPAP, PAWP, MRAP, and TPG between rest and exercise prior to HT for patients aged ≤50 years. §A statistically significant difference for MPAP, PAWP, MRAP, and TPG between rest and exercise prior to HT for patients aged >50 years. ‖A statistically significant difference for MPAP, PAWP, MRAP, and TPG between rest and exercise at 1 year after HT for patients aged ≤50 years. #A statistically significant difference for MPAP, PAWP, MRAP, and TPG between rest and exercise at 1 year after HT for patients aged >50 years. HT indicates heart transplantation; MPAP, mean pulmonary artery pressure; MRAP, mean right atrial pressure; PAWP, pulmonary artery wedge pressure; TPG, transpulmonary gradient.