Hemodynamic characteristics with regard to pulmonary and intracardiac pressures in the 94 patients at rest prior to and after HT. • Patients at rest. ○ Patients during exercise. Graphs show (A) MPAP, (B) PAWP, (C) MRAP (D) TPG, (E) PVR, and (F) TPVR at rest and during exercise before and after HT. *A statistically significant difference at rest compared with prior to HT. †A statistically significant difference at rest compared with 4 weeks after HT. ‡A statistically significant difference at rest compared with 4 weeks after HT. §A statistically significant difference during exercise compared with prior to HT. ‖A statistically significant difference during exercise compared with 4 weeks after HT. Of the 32 patients who exercised prior to HT, 16 exercised at 4 weeks, 22 at 3 months, 22 at 6 months, and 32 at 1 year after HT. HT indicates heart transplantation; MPAP, mean pulmonary artery pressure; MRAP, mean right atrial pressure; PAWP, pulmonary artery wedge pressure; PVR, pulmonary vascular resistance; TPG, transpulmonary gradient; TPVR, total pulmonary vascular resistance; WU, Wood units.