Table 2.
Factors Associated With Systemic Hypertension
| Parameter | OR | 95% CI | P Value |
|---|---|---|---|
| Univariate analysis | |||
| Age at CMR (per 1 year ↑) | 1.03 | 0.99 to 1.07 | 0.11 |
| Male gender | 1.02 | 0.44 to 2.39 | 0.95 |
| Age at repair (per 1 year ↑) | 1.01 | 0.97 to 1.05 | 0.68 |
| Second arch procedure | 1.27 | 0.59 to 3.04 | 0.59 |
| Ventricular septal defect | 1.79 | 0.58 to 5.45 | 0.31 |
| Bicommissural aortic valve | 0.96 | 0.42 to 2.20 | 0.91 |
| Arm-leg SBP gradient (per 1 mm Hg ↑) | 1.02 | 0.99 to 1.05 | 0.19 |
| Arm-leg SBP gradient at peak exercise (per 1 mm Hg ↑) | 1.02 | 1.00 to 1.05 | 0.02 |
| TAA/DAO diameter ratio (per 0.1 point ↓) | 1.36 | 1.03 to 1.81 | 0.02 |
| TAA CSA/BSA (per 0.5 cm2/m2 ↓) | 2.30 | 1.19 to 4.44 | 0.009 |
| Ratio of isthmus/DAO diameter ratio (per 0.1 point ↓) | 1.26 | 1.04 to 1.54 | 0.01 |
| Multivariable analysis (C-statistic=0.802) | |||
| TAA CSA/BSA (per 0.5 cm2/m2 ↓) | 6.41 | 1.72 to 23.8 | 0.006 |
| Age at CMR (per 5-year ↑) | 1.57 | 1.04 to 2.36 | 0.03 |
| Arm-leg SBP gradient at peak exercise (per 1 mm Hg ↑) | 1.03 | 1.01 to 1.05 | 0.05 |
BSA indicates body-surface area; CI, confidence interval; CMR, cardiac magnetic resonance study; CSA, cross-sectional area; DAO, descending aorta; OR, odds ratio; SBP, systolic blood pressure; TAA, transverse aortic arch.