Table 2.
Clinical and Biochemical Characteristics of the 116 Hypertensive Patients With and Without Arterial Stiffness
| Without Arterial Stiffness Group (n=33) | With Arterial Stiffness Group (n=83) | P Value | |
|---|---|---|---|
| Age, y | 65.4±12.0 | 62.9±11.2 | 0.305 |
| Gender, M/F | 18/15 | 42/41 | 0.837 |
| Smoke, Y/N (%) | 7 (21.2) | 17 (20.5) | 0.930 |
| BMI, kg/m2 | 23.29±2.93 | 23.72±2.45 | 0.456 |
| SBP, mm Hg | 145.2±20.4 | 143.5±19.2 | 0.670 |
| DBP, mm Hg | 76.1±7.4 | 82.8±12.4 | 0.001 |
| TC, mmol/L | 4.19±0.84 | 4.19±0.99 | 0.964 |
| LDL, mmol/L | 2.49±0.74 | 2.44±0.82 | 0.754 |
| TG, mmol/L | 1.74±0.85 | 1.51±0.70 | 0.173 |
| Cr, μmol/L | 57.94±12.20 | 65.45±14.44 | 0.006 |
| BaPWV, cm/s | 1239.33±109.19 | 1761.18±227.62 | <0.001 |
| ABI | 1.15±0.11 | 1.09±0.11 | 0.014 |
| Mimecan, ng/mL | 10.36±5.16 | 15.04±7.42 | <0.001 |
| ET-1, pg/mL | 2.02±0.76 | 2.63±1.09 | 0.001 |
| ACEI | 6 (18.2%) | 12 (14.5%) | 0.617 |
| ARB | 11 (33.3%) | 27 (32.5%) | 0.934 |
| Beta-blocker | 10 (30.3%) | 31 (37.3%) | 0.474 |
| CCB | 13 (39.4%) | 34 (40.9%) | 0.877 |
| Diuretic | 8 (24.2%) | 26 (31.3%) | 0.450 |
The data are presented as mean±SD, numbers, or numbers with percentages. P value for comparison between groups were determined using t test or chi-square test; P<0.05 was considered to be statistically significant. ABI indicates ankle-brachial pressure index; ACEI, angiotensin-converting enzyme inhibitors; ARB, angiotensin receptor blocker; baPWV, brachial-ankle pulse wave velocity; BMI, body mass index; CCB, calcium-channel blocker; Cr, creatinine; DBP, diastolic blood pressure; ET-1, endothelin 1; LDL, low-density lipoprotein; SBP, systolic blood pressure; TC, total cholesterol; TG, triglyceride.