Table 4.
Over-expression of collagens and collagen-modifying genes in the chicken oviduct
| Gene | Collagen type | Chain | WI/Ut (fold change)a | WI/Ma (fold change)a | Confirmed by Proteomics | |
| ESb membranes | ESb matrix | |||||
| COL1A1 | I | α-1 | - | 1.23 | - | [34] |
| COL1A2 | α-2 | - | 1.18 | [17] | [34, 38] | |
| COL2A1 | II | α-1 | - | - | - | [6, 35, 38] |
| COL3A1 | III | α-1 | - | 1.43; 1.16 | - | [34] |
| COL4A1 | IV | α-1 | - | - | - | - |
| COL4A2 | α-2 | - | - | - | - | |
| COL4A3 | α-3 | - | - | [17] | - | |
| COL5A1 | V | α-1 | - | - | - | - |
| COL5A2 | α-2 | - | - | [17] | [35] | |
| COL6A1 | VI | α-1 | - | - | - | [38] |
| COL6A2 | α-2 | - | - | [18] | [6, 35, 38] | |
| COL7A1 | VII | α-1 | - | - | - | [38] |
| COL8A1 | VIII | α-1 | - | - | - | - |
| COL10A1 | X | α-1 | 111.43; 50.21 | 155.42; 94.35 | [7, 17, 31] | [6, 35, 38] |
| COL17A1 | XVII | α-1 | - | - | - | [6, 38] |
| COL18A1 | XVIII | α-1 | - | - | - | [35] |
| COL20A1 | XX | α-1 | - | - | - | - |
| COL22A1 | XXII | α-1 | - | - | - | - |
| COL24A1 | XXIV | α-1 | - | - | [19] | - |
| Collagen-modifying enzymes | ||||||
| LOX | Lysyl Oxidase | - | - | - | - | - |
| LOXL1 | Lysyl oxidase-like 1 | - | ** | ** | - | - |
| LOXL2 | Lysyl oxidase-like 2 | - | 18.64 | - | [7, 17] | [6, 33, 38] |
| LOXL3 | Lysyl oxidase-like 3 | - | - | 1.27 | [17, 18, 31] | [38] |
| LOXL4 | Lysyl oxidase-like 4 | - | - | - | [19] | - |
| P4HA2 | Prolyl 4-hydroxylase | α-2 | 1.21 | 1.64 | - | - |
| P4HB | Prolyl 4-hydroxylase | β | - | 1.27 | - | [6] |
| PPIC | Peptidyl-prolyl cis-trans isomerase C | - | 1.28 | 1.51 | [17] | [6, 35, 38] |
a. **Expressed at very high (saturating) levels in all three tissues
b. ES - Eggshell