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FXIIIa inhibition does not reduce RBC retention in clots formed with Aα251 fibrinogen. Percent reduction in clot weight of contracted clots formed from TF-treated, recalcified fibrinogen-deficient plasma reconstituted with RBCs and platelets (2 million/μL and 200 000/μL, respectively), and γA/γA, γNNR, or Aα251 fibrinogen (0.25 mg/mL, final), in the absence or presence of 10 μM (final) T101 (n = 3-7 per fibrinogen). Bars are means ± SE.
