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. 2015 Oct 13;6:8533. doi: 10.1038/ncomms9533

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Co-staining with CD3 and B220 revealed that lung granulomas following infection with MtbΔsigH (a) exhibited a significantly increased iBALT response relative to infection with Mtb (b). White scale bar, 500 μm. Data from multiple lesions from six different animals were used in the analyses. (c) The percentage of area occupied by iBALT follicles relative to total lung area was analysed in animals challenged with Mtb (red) and MtbΔsigH (dark blue). *P<0.05 (Student's t-test). Data are means±s.d. Samples from four to five animals in each group were used for analysis.