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. 2015 Oct 13;6:8533. doi: 10.1038/ncomms9533

Figure 7. Bacterial burden following lethal Mtb challenge.

Figure 7

(a) Mtb CFU levels in total BAL samples at week 11 (3 weeks after challenge) and week 13 (5 weeks after challenge; (b). Mtb levels per gram of lung tissue at necropsy (c). Mtb burdens per gram of bronchial lymph node tissue at *P<0.05; **P<0.01; ***P<0.001; ****P<0.0001, (a) two-way ANOVA and (b,c) one-way ANOVA with Tukey's multiple testing correction. Data are means±s.d. Samples from all seven animals in each group were used for analysis at each time point. For analysis of lung burdens, four pooled samples (two each from left and right lung) from each macaque, each representing five distinct lung sections were used (b). For analysis of bronchial lymph node burdens, one section from each animal was analysed.