Table 3.
Effect of crude methanolic extract of the seeds of B. nigra on the mean survival times of P. berghei infected mice in both suppressive and prophylactic tests
| Tests | Treatments | Doses | Mean Survival Times (Days) |
|---|---|---|---|
| Suppressive | Distilled water | 10 ml/kg | 7.20 ± 0.37 |
| Brassica nigra seed extract | 100 mg/kg | 7.60 ± 0.25b2 | |
| 200 mg/kg | 9.00 ± 0.45a1,b2 | ||
| 400 mg/kg | 9.00 ± 0.71a1,b2 | ||
| Chloroquine | 10 mg/kg | 15.00 ± 0.00a2 | |
| Prophylactic | Distilled water | 10 ml/kg | 6.80 ± 0.20 |
| Brassica nigra seed extract | 100 mg/kg | 7.00 ± 0.32b2 | |
| 200 mg/kg | 7.60 ± 0.25b2 | ||
| 400 mg/kg | 7.80 ± 0.37b2 | ||
| Chloroquine | 10 mg/kg | 14.60 ± 0.40a2 |
Values are expressed as Mean ± SEM; n = 5. Where a = as compared to negative control; b = as compared to positive control; 1 = P < 0.05 and 2 = P < 0.001