Table 4.
Effect of crude methanolic extract of the seeds of B. nigra on the body weights of P. berghei infected mice in suppressive test
Treatments | Doses | Body Weight (gm) | ||
---|---|---|---|---|
D0-Weight | D4-Weight | Wt Change (%) | ||
Distilled water | 10 ml/kg | 29.64 ± 0.34 | 29.30 ± 0.32 | −1.15 |
Brassica nigra seed extract | 100 mg/kg | 30.38 ± 1.89 | 30.48 ± 2.05 | 0.33 |
200 mg/kg | 26.68 ± 1.57 | 26.92 ± 1.57 | 0.90a1 | |
400 mg/kg | 29.26 ± 1.41 | 29.62 ± 1.42 | 1.23a1 | |
Chloroquine | 10 mg/kg | 28.18 ± 1.64 | 28.58 ± 1.65 | 1.42a2 |
Values are expressed as Mean ± SEM; n = 5. Where a = as compared to negative control; 1 = P < 0.01 and 2 = P < 0.001