Table 5.
Effect of crude methanolic extract of the seeds of B. nigra on the body weights of P. berghei infected mice in prophylactic test
Treatments | Doses | Body Weight (gm) | ||
---|---|---|---|---|
D1-Weight | D7-Weight | Wt Change (%) | ||
Distilled water | 10 ml/kg | 24.94 ± 1.99 | 24.48 ± 2.00 | −1.84 |
Brassica nigra seed extract | 100 mg/kg | 26.80 ± 0.99 | 27.00 ± 0.94 | 0.75 |
200 mg/kg | 25.84 ± 2.42 | 26.06 ± 2.50 | 0.85 | |
400 mg/kg | 28.10 ± 1.56 | 28.42 ± 1.68 | 1.14 | |
Chloroquine | 10 mg/kg | 26.86 ± 1.13 | 27.34 ± 1.17 | 1.79a1 |
Values are expressed as Mean ± SEM; n = 5. Where a = as compared to negative control and 1 = P < 0.05