Table 4.
Univariate analysis of DFS and OS according to PELP1 protein expression in different subgroups
Variables | Subgroup | DFS | OS | ||
---|---|---|---|---|---|
χ 2 | P-value | χ 2 | P-value | ||
Age (years) | |||||
≤50 | 1.636 | 0.201 | 1.759 | 0.185 | |
>50 | 1.183 | 0.277 | 1.246 | 0.264 | |
Tumor size (cm)a | |||||
≤2 | 4.274 | 0.039 | 3.398 | 0.065 | |
>2, ≤5 | 0.441 | 0.507 | 0.813 | 0.367 | |
>5 | 1.936 | 0.164 | 1.134 | 0.284 | |
Lymph node stage | |||||
negative | 0.251 | 0.617 | 0.008 | 0.927 | |
positive | 0.770 | 0.380 | 1.974 | 0.160 | |
Grade | |||||
G1 | 1.864 | 0.172 | 0.688 | 0.407 | |
G2 | 2.369 | 0.124 | 2.327 | 0.127 | |
G3 | 0.188 | 0.665 | 0.461 | 0.497 | |
Clinical stagea | |||||
I | 1.231 | 0.267 | 1.250 | 0.264 | |
II | 0.258 | 0.612 | 0.009 | 0.926 | |
III and IV | 1.814 | 0.178 | 3.220 | 0.073 | |
Histological type | |||||
IDC | 1.278 | 0.258 | 1.399 | 0.237 | |
ILC | 1.780 | 0.182 | 1.591 | 0.207 | |
Others | 0.928 | 0.335 | 0.928 | 0.335 | |
Ki-67 LI | |||||
Low (≤14 %) | 0.148 | 0.700 | 0.161 | 0.688 | |
High (>14 %) | 5.069 | 0.024 | 5.559 | 0.018 | |
Chemotherapy | |||||
AC | 1.144 | 0.285 | 1.192 | 0.275 | |
AC-T | 1.910 | 0.157 | 1.871 | 0.171 | |
Others | 0.000 | 0.994 | 0.500 | 0.480 | |
Radiotherapy | |||||
No | 2.806 | 0.094 | 3.262 | 0.071 | |
Yes | 0.460 | 0.498 | 0.488 | 0.485 |
Abbreviations: LN, lymph node; IDC, invasive ductal carcinoma; ILC, invasive lobular carcinoma; Ki-67 LI, Ki-67 label index; AC, Adriamycin/Cyclophosphamide; AC-T, Adriamycin/Cyclophosphamide-Taxol; DFS, disease-free survival; OS, overall survival
Note: afor the variable, data for two cases are unavailable from medical records