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Effects of CHA on survival rates after 9-days monitoring of BALB/c mice. Survival percentage of BALB/c mice (N = 10) after challenged with intravenous injection of 2 × 109 CFU of S. aureus (WT) and ΔSrtA. Treatment with CHA (50 mg/kg, three times a day) was initiated after inoculation. Survival statistics were calculated by Log-rank (Mantel–Cox) test. The statistical significance determined as follows: WT vs. ΔSrtA, P < 0.0001; WT vs. WT+CHA, P < 0.05.
