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. Author manuscript; available in PMC: 2016 Jun 6.
Published in final edited form as: Lancet. 2015 Mar 4;385(9984):2264–2271. doi: 10.1016/S0140-6736(14)61730-X

Figure 2. Risk Ratios for Coronary Heart Disease with Statin Therapy across Genetic Risk Score Categories.

Figure 2

The boxes indicate the point estimates, and the size of each box reflects the weight of a trial's data within that subgroup. The horizontal lines display the 95% confidence intervals. The diamonds provide summary data. In PROVE IT-TIMI 22, the control group is moderate intensity statin therapy (pravastatin 40 mg) and the statin group is high intensity statin therapy (atorvastatin 80 mg).