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. Author manuscript; available in PMC: 2016 Nov 1.
Published in final edited form as: J Neuropathol Exp Neurol. 2015 Nov;74(11):1093–1118. doi: 10.1097/NEN.0000000000000255

Figure 10.

Figure 10

Myelin protein expression in humans is not affected by HIV status. Lysates from prefrontal cortex specimens of HIV-negative controls [(HIV (−)], and combined HIV-positive antiretroviral therapy cART-naïve and HIV-positive cART-medicated >12 months [HIV-+], were immunoblotted for myelin component proteins myelin basic protein (MBP), myelin oligodendrocyte glycoprotein (MOG), cyclic-nucleotide-3′phosphodiesterase (CNP), and myelin-associated glycoprotein (MAG) (n = 20 for each group). Protein expression levels were determined by quantification of band intensities normalized to a FastGreen total protein loading control. Patient samples were stratified by HIV status with HIV-negative individuals compared with the HIV-positive cases, both cART-naïve and cART-medicated combined, with red data points indicating patients diagnosed with HIV-Associated Neurocognitive Disorders (HAND). Black lines indicate mean ± SE. Student t-test determined statistical significance for direct comparisons, result was not statistically significant.