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. 2015 Oct;22(5):e336–e341. doi: 10.3747/co.22.2563

TABLE III.

Tumour markers in pleural fluida in cases of malignant and benign pleural effusions

Marker Case group p Value

Malignant (n=114) Benign (n=42)
Carcinoembryonic antigen (ng/mL) 14.0 (2.6–139.4) 1.3 (1.0–2.2) ≤0.001
Cancer antigen 15-3 (U/mL) 41.0 (14.0–190.0) 13.5 (10.2–21.6) ≤0.001
Carbohydrate antigen 19-9 (U/mL) 7.9 (2.1–38.0) 5.9 (1.8–12.0) 0.152
Cancer antigen 72-4 (U/mL) 7.1 (3.9–58.5) 6.8 (6.1–7.2) 0.059
Cancer antigen 125 (U/mL) 796.0 (258.0–1831.0) 86.5 (22.3–305.2) ≤0.001
CYFRA 21-1 (U/mL) 57.8 (18.7–271.3) 19.5 (10.3–47.4) ≤0.001
a

Values expressed as medians, with interquartile range in parentheses.