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. 2015 Oct;22(5):e342–e348. doi: 10.3747/co.22.2380

TABLE I.

Medication attributes and levels for the choice questions

Time until first skeletal-related event

  • ■ 28 Months

  • ■ 18 Months

  • ■ 10 Months

Time until a 2-point increase in pain on the BPI (“time until worsening of pain”)

  • ■ 10 Months

  • ■ 6 Months

  • ■ 3 Months

Risk of osteonecrosis of the jaw each year

  • ■ None

  • ■ 1 in 100 (1%)

  • ■ 5 in 100 (5%)

Risk of a 0.5 mg/dL increase in baseline creatinine each year (“risk of renal impairment each year”)

  • ■ None

  • ■ 4 in 100 (4%)

  • ■ 10 in 100 (10%)

Mode of administration and frequency (“mode of administration”)

  • ■ Daily oral tablet

  • ■ Injection every 4 weeks

  • ■ 15-Minute infusion every 4 weeks

  • ■ 120-Minute infusion every 4 weeks

BPI = Brief Pain Inventory.