Table 1.
Demographic and Clinical Characteristics of 27 Episodes of RGM Infection in 25 Patients
| Characteristic | |
|---|---|
| Median age, years (range) | 3.6 (0.9–17.1) |
| Male sex, number (%) | 15 (56) |
| Race, number (%) | |
| White | 25 (93) |
| African-American | 2 (7) |
| Other | 0 (0) |
| Cancer diagnosis, number (%) | |
| Hematological malignancy | 14 (52) |
| Solid tumor | 10 (37) |
| Brain tumor | 3 (11) |
| Median time since cancer diagnosis, months (range) | 9 (0–83) |
| No. receiving cancer chemotherapy in preceding month (%) | 15 (56) |
| No. receiving other immunosuppressive therapy (%) | 2 (7) |
| No. receiving corticosteroids in preceding month (%) | 12 (43) |
| Median duration of catheter use prior to infection, months (range) | 7 (1–23) |
| Median ANC, cells/mm3 (range) | 1900 (1–12 300) |
| No. patients with neutropenia (%) | 9 (33) |
| Median ALC, cells/mm3 (range) | 1218 (111–4018) |
| No. patients with lymphopenia (%) | 10 (37) |
| Type of infection, number (%) | |
| All catheter-related infections (%) | 23 (85) |
| Disseminated | 3 (13) |
| Disseminated + tunnel | 1 (4) |
| Non-disseminated bacteremia | 2 (7) |
| Non-disseminated bacteremia + tunnel | 1 (4) |
| Exit site infection | 8 (30) |
| Tunnel | 6 (26) |
| TID pocket | 2 (7) |
| Pulmonary | 2 (7) |
| Skin/soft tissue | 2 (7) |
| Causative species, number (%) | |
| M chelonae | 7 (30) |
| M abscessus | 6 (26) |
| M fortuitum | 6 (26) |
| M fortuitum/chelonae complex | 3 (11) |
| M mucogenicum | 2 (8) |
| M fluoranthenivorans | 1 (4) |
| M immunogenum | 1 (4) |
| M smegmatis | 1 (4) |
Abbreviations: ANC, absolute neutrophil count; ALC, absolute lymphocyte count; M, Mycobacterium; TID, totally implantable device.