Table 1.
Demographic data of patients studied
| (a) | Patients with SIRS | Healthy control subjects |
|---|---|---|
| n = 103 | n = 50 | |
| Age (years) | 57 ± 16 | 36 ± 10 |
| Male (%) | 60% | 40% |
| WBC × 109l | 18.3 ± 10.8 | 6.8 ± 2.4 |
| PMNs × 109l | 15.9 ± 11.4 | 4.1 ± 1.9 |
| Platelets × 109/l | 203 ± 129 | NT |
| CRP (μg/ml) | 152 ± 87 | < 1 |
| Survival after 28 days | 74% | n.a. |
| Apache II score | 18 ± 5 | n.a. |
| (b) Categorization of patients with sepsis (n = 83) | |||
|---|---|---|---|
| Microbiological confirmation | Clinical suspicion | ||
| Gram-negative (n = 23) | Gram-positive (n = 34) | n = 26 | |
| Bacterioides fragilis | Streptococcus pyogenes | ||
| Escherichia coli | Enterococcus sp. | ||
| Klebsiella sp. | Staphylococcus aureus (MRSA) | ||
| Morgonella sp. | Staphylococcus aureus | ||
| Serratia marcescens | Staphylococcus epidermidis | ||
| Pseudomonas aeruginosa | Streptococcus pneumonia | ||
Results are expressed as means ± standard deviation; n.a. = not applicable; NT = not tested; MRSA = methicillin-resistant Staphylococcus aureus; APACHE = Acute Physiology and Chronic Health Evaluation.