Table 2.
Genotypical and allelic frequencies of different matrix metalloprotease (MMP) single nucleotide polymorphisms (SNPs) according to gender
| Genotypical frequencies | Allelic frequencies | |||||||
|---|---|---|---|---|---|---|---|---|
| SNP | Genotype | Male n (%) | Female n (%) | P | Allele | Male n (%) | Female n (%) | P |
| MMP-1 (-1607 1G/2G) | 1G1G | 44 (26·5%) | 28 (28·9%) | 0·078 | 1G | 149 (44·9%) | 79 (40·7%) | 0·4 |
| 1G2G | 61 (36·7%) | 23 (23·7%) | 2G | 183 (55·1%) | 115 (59·3%) | |||
| 2G2G | 61 (36·7%) | 46 (47·4%) | ||||||
| MMP-3 (-1612 5A/6A) | 5A5A | 31 (28·4%) | 23 (34·3%) | 0·7 | 5A | 113 (51·8%) | 75 (56·0%) | 0·5 |
| 5A6A | 51 (46·8%) | 29 (43·3%) | 6A | 105 (48·2%) | 59 (44·0%) | |||
| 6A6A | 27 (24·8%) | 15 (22·4%) | ||||||
| MMP-8 (-799C/T) | CC | 52 (26·8%) | 24 (21·8%) | 0·6 | C | 195 (50·3%) | 102 (46·4%) | 0·4 |
| CT | 91 (46·9%) | 54 (49·1%) | T | 193 (49·7%) | 118 (53·6%) | |||
| TT | 51 (26·3%) | 32 (29·1%) | ||||||
| MMP-9 (-1562 C/T) | CC | 152 (79·2%) | 88 (80·7%) | 0·7 | C | 343 (89·3%) | 197 (90·4%) | 0·7 |
| CT | 39 (20·3%) | 21 (19·3%) | T | 41 (10·7%) | 21 (9·6%) | |||
| TT | 1 (0·5%) | 0 (0·0%) | ||||||
| MMP-13 (-77A/G) | AA | 123 (59·7%) | 77 (64·7%) | 0·5 | A | 328 (79·6%) | 196 (82·4%) | 0·4 |
| AG | 82 (39·8%) | 42 (35·3%) | G | 84 (20·4%) | 42 (17·7%) | |||
| GG | 1 (0·5%) | 0 (0·0%) | ||||||