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. 2015 Oct 16;10(10):e0140772. doi: 10.1371/journal.pone.0140772

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Fig 4 — The rats in saline groups were combined for analysis, as they were not statistically different. (A) Representative coronal brain sections stained with cresyl violet. (B) A151 reduced infarct volumes in male rats. (C) A151 reduced infarct volumes in female rats. (D) A151 improved performance in forepaw test in female rats. (E) A151 reduced brain NLRP3 mRNA 48 hours after pMCAO, the error bars represent the 95^th upper and lower confidence intervals of gene expression. (n = 7–17 per group; *, p < 0.05 compared with saline control; **, p < 0.05 compared with saline control or C151).