Table 5. Protein families with Identified Motifs using MEME/MAST.
Protein families demonstrating shared, conserved residues are shown below. HMMTOP was used to predict the TMS location for each motif. Schematic diagrams showing the motif locations and other highly conserved residues are found in Fig 3A–3G.
| Families | Predicted TMS region | # Proteins displaying motif/# Total Proteins | Motif |
|---|---|---|---|
| CaCA2 & ILT | #3 of both | 80/80 (40 ILT, 40 CaCA2) | FGX(K/R)XL |
| CadD & MntP | #4 of both | 170/170 (85 CadD, 85 MntP) | Fully conserved D |
| CadD & MntP | #6 of both | 170/170 (85 CadD, 85 MntP) | Conserved G |
| CadD & MntP | #1 of both | 170/170 (85 CadD, 85 MntP) | Fully conserved D |
| TerC & LysE | #3 of both | 248/248 (124 LysE, 124 TerC) | GXXXL |
| TerC & RhtB | #3 of both | 176/176 (88 TerC, 88 RhtB) | GXXYL |