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. 2015 Oct 12;10:6455–6467. doi: 10.2147/IJN.S92019

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© 2015 Neacsu et al. This work is published by Dove Medical Press Limited, and licensed under Creative Commons Attribution – Non Commercial (unported, v3.0) License

The full terms of the License are available at http://creativecommons.org/licenses/by-nc/3.0/. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed.

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Nitrite concentrations in the cell culture media of LPS-stimulated macrophages under influence of selective inhibitors of p38 (SB202190), ERK1/2 (U0126), and JNK (SP600125).

Notes: Cells were allowed to adhere on the samples for 18 hours, then were incubated with selective MAPK inhibitors for 1 hour and further treated with 1 µg·mL⁻¹ LPS for 24 hours. Nitrite accumulation in cell culture media was assessed by Griess reaction. The data are expressed as mean ± SD. *P<0.05; ***P<0.001.

Abbreviations: cpTi, commercial pure titanium; JNK, c-Jun NH₂-terminal kinase; LPS, lipopolysaccharide; MAPK, mitogen-activated protein kinase; ERK, extracellular signal-regulated kinase; SD, standard deviation.