Table 4. Gene expression levels in Th2-polarized cells exposed to Copaxone and Glatopa vs media alone.
| Symbol | Gene Name | Copaxone log2 fold difference* | Glatopa log2 fold difference* |
|---|---|---|---|
| CCR2 | Chemokine (C-C motif) receptor 2 | –0.7 | –0.7 |
| CXCL10 | Chemokine (C-X-C motif) ligand 10 | –0.8 | –0.8 |
| CXCR3 | Chemokine (C-X-C motif) receptor 3 | –0.6 | –0.6 |
| H2-Eb2 | Histocompatibility complex class II antigen E beta 2 | –0.3 | –0.3 |
| HLADMA | Major histocompatibility complex class II, DM alpha | 0.8 | 0.8 |
| HLADMB | Major histocompatibility complex class II, DM beta | 1.0 | 0.9 |
| HLADQB1 | Major histocompatibility complex class II, DQ beta 1 | 0.6 | 0.7 |
| ICOSLG | Inducible T-cell costimulatory ligand | –1.9 | –1.9 |
| IL-10 | Interleukin-10 | 0.7 | 0.8 |
| IL-12RB1 | Interleukin-12 receptor, beta 1 | 1.1 | 1.2 |
| IL-13 | Interleukin-13 | 4.1 | 4.0 |
| IL-2RA | Interleukin-2 receptor, alpha | 0.6 | 0.7 |
| IL-2RB | Interleukin-2 receptor, beta | 1.0 | 1.2 |
| IL-3 | Interleukin-3 | 3.7 | 3.9 |
| IL-4 | Interleukin-4 | 2.4 | 2.6 |
| IL-5 | Interleukin-5 (colony-stimulating factor, eosinophil) | 2.4 | 2.5 |
| IL-6 | Interleukin-6 (interferon, beta 2) | 1.1 | 1.3 |
| LTB | Lymphotoxin beta (tumor necrosis factor superfamily, member 3) | –1.0 | –1.1 |
| S100A10 | S100 calcium-binding protein A10 | –1.3 | –1.2 |
Th, T-helper.
*Log2 of the fold difference in mean expression for the indicated test material compared with media alone.