Table 2. Comparison of fasting serum levels of sCD26/DPP-IV and active GLP-1 between normal, non-diabetic metabolic syndrome, type 2 diabetes mellitus subjects with and without metabolic syndrome and total type 2 diabetes mellitus.
| Non-diabetes n = 235 | Type 2 diabetes n = 314 | Total type 2 diabetes | |||||||
|---|---|---|---|---|---|---|---|---|---|
| Parameters | Normal Control n = 164 | MetS n = 71 | P-Value | Without MetS n = 57 | P-Value | With MetS n = 257 | P-Value | Total type 2 diabetes n = 314 | P-Value |
| sCD26/DPP-IV (ng/mL) | 1089 (281) | 1120 (275) | a 0.427 | 1195 (204) | a 0.015, b 0.139 | 1199 (245) | a 1.2×10 −4, b 0.041, c 0.933 | 1198 (239) | a 5.7×10 −5, b 0.038 |
| Active GLP-1 (pmol/L) | 4.26 (3.89) | 3.94 (3.71) | a 0.340 | 3.53 (2.24) | a 0.028, b 0.270 | 3.74 (2.29) | a 0.020, b 0.487, c 0.479 | 3.71 (2.28) | a 0.010, b 0.397 |
The results presented represent geometric means (SD), adjusted for age, race and gender.
avs control group
bvs non-diabetic metabolic syndrome group
cvs type 2 diabetes mellitus without metabolic syndrome which evaluated using univariate (General Linear Model).
Bold values are significant. MetS: metabolic syndrome.