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. 2015 Oct 16;10(10):e0140910. doi: 10.1371/journal.pone.0140910

Fig 2. Islet residual rate, viability, and stimulation index following culture with or without Matrigel.

Fig 2

Islets were cultured for 96 h with or without Matrigel before the assessment of residual rate, viability, and the ratio of insulin released in response to stimulation by high and low concentration glucose solutions (SI). (A) The residual rate of islets in the GFR Matrigel or Matrigel groups was significantly higher than that in the islets-only group. (B) Islet cell viability in GFR Matrigel or Matrigel groups was significantly higher than that in the islets-only group. Right figures; green: viable cells, red: dead cells. Scale bar, 100 μm. (C) The SI was significantly higher in the GFR Matrigel and Matrigel groups compared with the islets-only group. *P < 0.05. GFR, growth factor reduced; SI, stimulation index.