Fig 5. Alignment of M. tuberculosis DprE1 ortholog proteins in Nocardia spp. We observe that all species have orthologs with the susceptible genotype, a cysteine at position 368.

This analysis included common Nocardia pathogens, such as N. brasiliensis, N. cyryiacigeorgica, N. farcinica, N. transvalensis, and N. otitidiscaviarum. We also included rarely pathogenic species, such as N. tenerifensis, N. terpenica, and N. carnea.