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ACTH antagonists and their inhibition of [3H] ACTH11-24 in rat adrenal cortex membranes by unlabeled peptides.
| Compound | Peptide sequence | IC50 (nM) | Ki (nM) |
|---|---|---|---|
| ACTH1-24 | SYSMEHFRWGKPVGKKRRPVKVYP | ||
| ACTH11-24 | KPVGKKRRPVKVYP | 11.3 | 1.7 |
| ACTH15-18 | KKRR | 15.1 | 2.3 |
| pIL-1α81-88 | GKPVGKKRR | 7.6 | 2 |
