Table 1. DBA patient and healthy donor demographics.
| Age | Sex | Ethnicity | Gene Mutation | Treatment | Hb* (g/dL) | Erythrocytes*(MIL/μL) | MCV* (fL) | |
|---|---|---|---|---|---|---|---|---|
| D1 | 32 | F | Caucasian | RPS19, nonsense | None† | 4.7, 10.4 | 1.1, 2.5 | 116, 119 |
| D2 | 22 | F | Caucasian | RPL5, splice site | None† | 10.2, 10.6 | 3.1, 3.3 | 93, 93 |
| D3 | 17 | M | Caucasian | Unknown | Prednisone | 8.6, 7.0 | 2.3, 1.9 | 115, 117 |
| D4 | 16 | M | Caucasian | RPS19, splice site | Prednisone | 13.5, 14.3 | 4.2, 4.3 | 93, 96 |
| D5 | 14 | M | Caucasian | RPL11, frame shift | Prednisone | 11.5 | 3.7 | 98 |
| D6 | 22 | F | Caucasian | RPS17, frame shift | Prednisone | n.d, 14.6 | n.d, 4.2 | n.d, 98 |
| C1 | 24 | F | Caucasian | |||||
| C2 | 28 | F | Caucasian | |||||
| C3 | 33 | F | Caucasian | |||||
| C4 | 21 | M | Caucasian | |||||
| C5 | 22 | M | Caucasian | |||||
| C6 | 20 | M | Caucasian |
*Two values were from separate blood draws at two different times that were used for the replicate proteome analyses designated as a and b, respectively
n.d—not determined.
Normal values for: Hb—13.5–17.5 males, 12.0–15.5 females; Erythrocytes—4.3–5.7 males, 3.9–5.0 females; mean corpuscular volume (MCV)—80–100 for male and female.
†Patients D1 and D2 were transfused in the past.