Skip to main content
. 2015 Oct 16;10(10):e0135076. doi: 10.1371/journal.pone.0135076

Fig 1. Minor Allele Frequency Differences in EU and AA.

Fig 1

Results of polymorphisms identified by NGS are mapped to the reference human genome used by the 1000 Genomes project (hg18). Vertical lines indicate the Δ MAF (difference between the minor allele frequency in cases versus controls) for each base pair of the genome region investigated. Higher peaks indicate a greater difference in prevalence of that variation between cases and controls, and thus a higher potential for association with schizophrenia risk. The red graph indicates data for Whites and the Blue graph indicates data for African Americans. (A) Δ MAF map for the EGR3 locus, hg18 coordinates chr8:22,591,791–22,612,066. (B) Δ MAF map for the ARC locus, hg18 coordinates chr8:143,682,474–143,697,026