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. 2015 Oct 16;10(10):e0140794. doi: 10.1371/journal.pone.0140794

Table 2. Adverse events associated with treatment.

Chemotherapy Chemotherapy plus icotinib
(n = 18) (n = 21)
n (%) n (%)
Grade 1 Grade 2 Grade 1 Grade 2
Gastrointestinal reactions 3 (16.7%) 1 (5.6%) 3 (14.3%) 0
Marrow suppression 3 (16.7%) 0 (0.0%) 4 (19.0%) 0
Neurotoxicity 3 (16.7%) 1 (5.6%) 4 (19.0%) 0
Liver and kidney damage 2 (11.1%) 1 (5.6%) 4 (19.0%) 0
Allergic reactions 2 (11.1%) 1 (5.6%) 3 (14.3%) 0