Table 3. Intra-assay variation comparison of Hi3 peptide quantitation to targeted proteomics studies of plasma proteins.
| Source of Data | Intra-assay CV | CV≤ 20% | CV≤ 30% |
|---|---|---|---|
| HI3 peptide quantitation data from this study. | 16% (6–64%) | 82% | 90% |
| Targeted Proteomics study [12] using isotopic labels. | 8% (7–12%) | 100% | 100% |
| Targeted Proteomics study [16] using isotopic labels. | 6% (1–18%) | 100% | 100% |
| Targeted Proteomics study [15] using isotopic labels. | 5% (1–20%) | 100% | 100% |
| Targeted Proteomics study [13] using isotopic labels. | 9% (5–60%) | 93% | 98% |
| Targeted Proteomics study [14] without isotopic labels. | 12% (5–40%) | 76% | 88% |
Range of minimum to maximum value of the CV is shown between brackets.