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. 2015 Oct 16;10(10):e0141033. doi: 10.1371/journal.pone.0141033

Table 2. Results of QuantiFERON-TB Gold In-Tube and T-SPOT.TB tests in initial evaluation of LTBI in patients with rheumatic diseases scheduled for TNF-α antagonist therapy.

QFT-GIT
T-SPOT.TB Positive Negative Indeterminate a Total
Positive 41 28 1 b 70
Negative 4 74 2 80
Indeterminate a - 6 - 6
Total 45 108 3 156

LTBI, latent tuberculosis infection; TNF, tumor necrosis factor; QFT-GIT, QuantiFERON-TB Gold In-Tube.

aAll QFT-GIT indeterminate results occurred due to failure to generate an IFN-γ response to mitogens, and all T-SPOT.TB indeterminate results were due to excessive response of negative controls.

bOne QFT-GIT-indeterminate patient with a 10 mm tuberculin skin test result received TB medication.