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. Author manuscript; available in PMC: 2016 Oct 7.
Published in final edited form as: ACS Appl Mater Interfaces. 2015 Sep 23;7(39):22058–22066. doi: 10.1021/acsami.5b07254

Figure 6.

Figure 6

Shear-induced platelet activation in the HSD. GFP were exposed to 1 dyne/cm2 or 20 dyne/cm2 for 12 min in the HSD, with samples drawn every 4 min for the PAS assay. (A) PAS was observed to increase over the duration of the experiment, with the change in PAS (ΔPAS) over 12 min largest in the high flow rate regimes. (B) While the largest changes in PAS (ΔPAS) were measured for PCL and xSIBS at 20 dyne/cm2, no significant difference was observed (p > 0.05). The mean ΔPAS for xSIBS was slightly above the threshold observed for shear-induced platelet sensitization (dashed black line26).