Mean ±se overall percentage correct by rats as a function of concentration for Polycose (left) and for sucrose (right) in T1R2 knock-out (KO) and wild type (WT) mice in a two-response taste detection task. Replotted from Treesukosol Y, Spector AC. (2012). Orosensory detection of sucrose, maltose, and glucose is severely impaired in mice lacking T1R2 or T1R3, but Polycose sensitivity remains relatively normal. American Journal of Physiology - Regulatory, Integrative and Comparative Physiology 303: R218–R235 with permission.